comparison of the acute broncho dilating effects of inhaled ipratropium bromide and salbutamol in patients wi th chronic obstructive pulmonary dise ase

نویسندگان

s mohamedi from the tehran university of medical sciences, tehran, and the *dept. of pharmacology, shaheed beheshti university of medical sciences, tehran, i.r. iran.

f roshanzamir

a mahdavi

mh pourgholami

چکیده

forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (fev 1) and forced vital capacity (pvc). ipratropium bromide produced a significantly greater improvement than salbutamol in both fev1 and fvc at 15,60 and 180 minutes after drug administration. it may therefore be concluded that in patients with chronic obstructive pulmonary disease, ipratropium bromide has greater potency and a longer duration of action than salbutamol

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COMPARISON OF THE ACUTE BRONCHO DILATING EFFECTS OF INHALED IPRATROPIUM BROMIDE AND SALBUTAMOL IN PATIENTS WI TH CHRONIC OBSTRUCTIVE PULMONARY DISE ASE

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عنوان ژورنال:
medical journal of islamic republic of iran

جلد ۱۱، شماره ۲، صفحات ۱۱۱-۱۱۴

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